Well for one it is more difficult to search accurately and efficiently for files, apps, and other various files and folders. Also, there are some features that work flawlessly with Windows 7 that do not work as good or do not exist in Window 8, such as gpedit.msc features (accessible on Windows 8 Pro, however) and Aero is non-existent in Windows 8, which I loved the blur effect demonstrated on Windows 7 by default. Also on an actual Windows 8 laptop (like mine), standard buttons such as F1, F4, F12, etc. are only accessible by holding the function (Fn) key, and Mac-like features are usable by default, which is a bit annoying, especially when playing games such as Minecraft. And you also lose Desktop games that have been on Windows since early versions like Solitaire, Minesweeper, Chess, Checkers, etc. and now they can only be acquired on the Start Screen by downloading apps for them, and you still don't get all the features included.
But of course there are many upsides such as email notifications, chat, etc., faster, more up-to-date, and other things..